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A Randomized Controlled Clinical Study of Karanjadhya Ghrita in the management of Dushta Vrana (chronic wounds)

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Dr Neelam Choudhary1, Dr Prashant Soni2, Dr Madhusudan Swarnkar3

Paper Index :05.2015-xxxxxxx

1MD (Rasa Shastra & Bhaishajya Kalpana)

Affiliation - P.G. Department of Rasashastra & Bhaishajya Kalpana,

National Institute of Ayurveda, Jaipur 302002

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2MBBS, MBA

Affiliation – National Advisor (Quality Improvement), USAID ASSIST Project, University Research Company, Delhi.

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3MD (Community  Medicine)

Affiliation – Associate Professor, Dept. of Community Medicine,

Jhalawar Medical College, Jhalawar.

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Corresponding author:

  1. Dr Neelam Choudhary, MD (Rasa Shastra & Bhaishajya Kalpana)

Affiliation - P.G. Department of Rasashastra & Bhaishajya Kalpana,

National Institute of Ayurveda, Jaipur 302002

 

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Abstract

Background: Dushta Vrana (Chronic wounds) are frequently encountered problem in the present era produced due to the complications of trauma or pathological injury and it causes long-term agony to the patients. Chakradutt has mentioned the wound healing properties of Karanjadhya Ghrita. In the present study Karanjadhya Ghrita was prepared and its wound healing properties were studied on various chronic wounds.

Methods:

Karanjadhya Ghrita was prepared using the standardization procedure the effects were studied on 40 patients with chronic wounds (wounds more than 3 weeks old) selected from Outpatient and inpatient department of department of Shalya Tantra, National Institute of Ayurveda, Jaipur. The patients were divided into two groups – Group A (Karanjadhya Ghrita dressing) and Group B (Hydrogen peroxide and EUSOL and dry Gauze bandage). The drug was applied topically and patients were studied daily for 30 days and results were analyzed.

Results:

In Chronic Wound the size was decreased 69.23% which was statistically highly significant. There was considerable improvement (> 80 %) in swelling and unhealthy margin. Pain, tenderness, discharge and unhealthy granulation tissue showed moderate effect (between 60 to 70 percent) in the chronic wounds

Conclusion:

From the studies made from clinical cases, it was concluded that, the drug “Karanjadhya  Ghrita” possess sufficient efficacy in Vrana Shodhan and Vrana Ropana properties without producing any adverse effects. The drug also increase the rate of contraction produces healthier granulation tissue and rapid healing time. Hence, this study conclude that application of Karanjadhya Ghrita is highly effective on chronic wounds.

 

 

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Category: Volume 5 Issue 3 [May-June 2015]