1Priyanka Shivanand. Mds Post Graduate, 2Vandana Kv. Mds Professor, 3Shobha Prakash. Mds
Paper Index :
1,2,3Department of Periodontics, College Of Dental Sciences, Davangere-577 004
E-mail address: 1This email address is being protected from spambots. You need JavaScript enabled to view it., 2This email address is being protected from spambots. You need JavaScript enabled to view it., 3This email address is being protected from spambots. You need JavaScript enabled to view it.
Corresponding Author:Dr. Priyanka Shivanand
Department(S) And Institution(S) :Department Of Periodontics. College Of Dental Sciences, Davangere
Address: room no 4, Department of Periodontics, College of dental sciences, Davangere-577004
E-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Gumtone™(Acacia arabica), a polyherbal gel, has found to be effective as an antiplaque and antibacterial agent for gingivitis however its effect against periodontal pathogens is not known which causes periodontal diseases. The study was conducted to determine the antimicrobial activity of Gumtone™(Acacia arabica) against the periodontal pathogens.
The inhibitory effect and the time-kill curve of Acacia Arabica gel (Gumtone™)on Aggregatib -acteractinomycetemcomitans (Aa), Porphyromonasgingivalis(Pg) and Prevotellainter media (Pi) was evaluated. The inhibitory and growth time kill curve were determined using serial dilution methods at 0, 2, 4, 6 and 24hrs.The Gumtone™ showed bacteriostatic and bactericidal activity against the Aaand Pg with minimum inhibitory concentration (MIC) at 0.8 µl/ml, 0.4µl/ml respectively, better bactericidal against Pg.The study shows that Gumtone™has antimicrobial activity against periodontal pathogens like P. gingivalis, A. actinomycetemcomitans,and this raises the possibility that Gumtone™may have therapeutic use for periodontitis in clinical practice.
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