1Saroj Kumar Debnath  ,  2Dipsundar Sahu , 3Debajyoti Das ,4Laxmidhar Barik , 5M M Rao

DOI : http://dx.doi.org/10.31142/ijahm/v8i6.02

            1.Research Officer (Ayurveda), Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences,  Ministry of AYUSH, Government of India. 

2Research Officer (Ayurveda), Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences,  Ministry of AYUSH, Government of India.

3Research Officer (Ayurveda), Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences,  Ministry of AYUSH, Government of India.

4Research Officer (Ayurveda), Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences,  Ministry of AYUSH, Government of India.

5Director, Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences,  Ministry of AYUSH, Government of India. 

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Abstract:

Ayurveda accepts all dravyas (substances) are panchabhautika (five elements) and dravya (substances) has the medicinal properties. Ama (biotoxin) and vitiated Vata (bioforce) are the main causative factor in the disease manifestation of Amavata (Rheumatoid arthritis). One important plant based Ayurvedic drug i.e. Alambushadi Churna have been selected from famous Ayurvedic book (i.e. Bhava Prakasha) in context of Amavata for its probable standardization. It is a poly herbal Ayurvedic drug. The Rasa, Guna, Virya, Vipak and Karma of ingredients of Alambushadi Churna help to reduce the clinical manifestations of Amavata (Rheumatoid arthritis). The Physico-chemical study revealed that the Alambushadi Churna tablet contained more moisture, less inorganic constituents and more water soluble constituents. The Phytochemical study revealed that reducing sugars, tannin, phenolic compounds, flavonoids, saponin, glycosides and gum were present into the sample of Alambushadi Churna tablet. Four phytocostitutents were indicated under short ultra violet ray (254 nm) and five phytocostitutents were indicated under long ultra violet ray (366 nm) by thin layer chromatography study on the sample of Alambushadi Churna tablet. 

KEY WORDS: Alambushadi Churna tablet, Amavata, Rheumatoid arthritis.

REFERENCE

1.      Agnivesh, Charak, Drdhabala, Tripathi B. Charak Smhita with Charak Chandrika hindi commentary (part-I, Sutra sthan 26/12). 1st ed. Varanasi: Chaukhamba Surbharati Prakasan; 1983.

2.      Madhavakara, Rakshita V, Dutta S, Shastri  S. Madhava Nidana with Madhukokosha Vyakya and Vidyotini Hindi Commentry (Part-I). Edited by Yadunandan Upadhyaya. 26th ed. Varanasi: Chaukhambha Sanskrit Sanathana; 1996. p. 460-464.

3.      Harrison TR. Harrison’s Principles of Internal Medicine (Vol-2). Edited by Anthony S. Fauci et al. 14th ed. New-York: Mc Graw-Hill; 1998. p. 1885.

4.   Bhavamishra. Bhavaprakasha with Vidyotini Hindi Commentary (Part-II). Edited by Brahma Sankara Mishra. 9th ed. Varanasi: Chaukhambha Sanskrit Sansthana; 2005. p. 287.

5.      Sharma PV. Dravyaguna Vijnana (Vol. I, II). 8th ed. Varanasi: Chaukhambha Bharati Academy; 1986.

6.      Dhyani SC. Rasa-Panchak. 2nd ed. Varanasi: Chaukhambha Krisnadas Academy; 2000.

7.      Chopra RN. Indigenous Drugs of India. 2nd ed. Calcutta: U. N. Dhur and Sons Pvt. Ltd.; 1959.

8.      Harborne JB. Phytochemical methods. 2nd ed. Landon: Chapman and Hall; 1984.

9.   Debnath SK. Alambushadi Churna-A good Drug for Amavata (Rheumatoid Arthritis) Management- A Classical Review, International Journal of Applied Ayurved Research, Volume II, Issue 5, Jan-Feb 2016, 647-651.

10.  Debnath SK, Vyas SN. Physico-Chemical Study on Alambushadi Churna Tablet, International Journal of Ayurveda and Pharmaceutical Chemistry, Volume 3, Issue 1, 2015,139-143.

11.  Debnath SK, Vyas SN. Phytochemical Study on Alambushadi Churna Tablet, International journal of Ayurvedic & Herbal medicine, Volume 5, Issue 4, July-Aug 2015, 1849-1852.

12.  Debnath SK, Vyas SN. Thin Layer Chromatography Study on Alambushadi Churna Tablet, International Ayurvedic Medical JournalVolume 3, Issue 9, September- 2015, 2850-2853.