GC-MS Analysis of Root And Aerial Parts Ethanolic Extract of Phyllanthus Vasukii Parthipan Et Al., Sp. Nov. (Phyllanthaceae)

Published: Saturday, 13 September 2014 10:43 | Written by Super User | Print | Email | Hits: 6574

¹Jemimma, H. L., ²Arumugasamy K , ³Nantha Kumar. R. , ⁴Abdul Kaffoor H.

DOI : http://dx.doi.org/10.18535/ijahm/v7i4.06

Department of Botany, Kongunadu Arts and Science College (Autonoumous), Coimbatore, Tamilnadu, India

ABSTRACT:

Objective: The objective of this research is to determine the possible bioactive components of the root and aerial parts of Phyllanthus vaukii using GC-MS analysis.

Methods: The GC-MS analysis of these extracts were performed using a Perkin-Elmer GC Clarus 500 system and Gas chromatograph interfaced to a Mass spectrometer (GC-MS) equipped with a BR-5MS, fused silica capillary column (30mm × 0.25mm 1D × 0.25 µMdf, composed of 5% Diphenyl / 95% Dimethyl poly siloxane).

Results: From P. vasukii root and aerial parts, thirty (30) and twenty seven (27) components were identified respectively. Of the 30 compounds eluted from the root extract, stigmasterol had the highest peak area of 18% and the lowest was n-Propyl 11-octadecenoate showing 0.38%. In the aerial extract 1,2,3-Benzenetriol had the highest peak area of 31.65% and Z,Z-3,15-Octadecadien-1-ol acetate with the lowest peak area of 0.19%. These results indicate the ethanol extract of P. vasukii aerial and root parts possess potent antioxidant, hepatoprotective, anti-inflammatory, antiarthritic, antioxidant, anticancer, Immunostimulant, antitumour, cancer preventive, antiarthritic, antidiabetic, antimicrobial effects so that it can be recommended as a plant of pharmaceutical importance.

Conclusion: However, isolation of individual phytochemical constituents may proceed to find a novel drug or lead compound.

Keywords- Phyllanthus vasukii (P.vasukii), Gc-Ms Analysis, Bioactive Compound, root and aerial parts, ethanolic extract

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Category: Volume 7 Issue 4 [July -Aug. 2017]

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GC-MS Analysis of Root And Aerial Parts Ethanolic Extract of Phyllanthus Vasukii Parthipan Et Al., Sp. Nov. (Phyllanthaceae)

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id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	a	NULL	ref	idx_access,idx_state,idx_catid,idx_language	idx_catid	4	const	33	16.00	Using index condition; Using where; Using filesort
1	SIMPLE	cc	NULL	const	PRIMARY	PRIMARY	4	const	1	100.00	NULL

id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	m	NULL	ref	PRIMARY,published,newsfeeds,idx_language	published	1	const	12	3.33	Using index condition; Using where; Using filesort
1	SIMPLE	e	NULL	ref	element_clientid,element_folder_clientid	element_clientid	403	rajourna_ijahm.m.module,const	1	10.00	Using index condition; Using where
1	SIMPLE	mm	NULL	ref	PRIMARY	PRIMARY	4	rajourna_ijahm.m.id	1	40.00	Using where; Using index