Scientific Exploration of Ingredients of katak Khadiradi Kashyayamfor Their Anti Diabetic Property

Published: Saturday, 13 September 2014 10:43 | Written by Super User | Print | Email | Hits: 6086

¹Dr Kolhe NS, ²Dr Bapat VA

DOI : http://dx.doi.org/10.18535/ijahm/v7i4.22

¹Associate Professor department of Rog evam vikriti Vigyan SKAM College Chilapur,Varanasi.

²Panchakarma Vaidya PG Department of Panchakarma National Institute of Ayurveda Jaipur.

ABSTRACT:

Background:-A huge number of drugs are prescribed by Ayurvedic physicians to the patients of diabetes-like diseases and number of preparation are traditionally used by different school of practitioners, since thousands of years. Among them Katak Khadiradi Kashayamhas been advocated in Sahasra Yogam(A popular book on Kerliya tradition of Ayurvedic treatment). Andis being practiced in Southern part of India,since two hundred years to treat Diabetes Mellitus. Though principally its mode of action is well established as per Ayurvedic parameters, it is a need of time to establish this on the basis of modern biochemical and pharmacological parameters.

Methods:-we searched Pubmed and scholarly articles with the help of google search engine to see that is there any kind of alkaloid present in any drug of this combination which shows antidiabetic or hypoglycemic effect.For this each drug of this combination is studied separately on the basis of previous researches especially animal experiments and data is gathered.

Results:- Extract of almost each drug shows anti-hyperglycemic effect along with rejunuvative and antioxidant properties in experimental or animal studies.

Conclusion:-Hence, Katak Khadiradi Kashayam has an effect on protecting β-cells and smoothing out fluctuation in glucose levels. shows antidiabetic effect along with antioxidant property which can be very helpful for diabetes Mellitus.

Key words: - Ayurveda ,Katak Khadiradi Kashayam ,Diabetic Mellitus..

Reference:

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17. Rai PK, Jaiswal D, Mehta S, Rai DK, Sharma B, Watal G.Effect of curcuma longa freez dried rhizome powder with milk in stz induced diabetic rats. Indian Journal of Clinical Biochemistry Apr 2010 25(2):175-181

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20. Hossain MS, Khan MRI, Anisuzzaman ASM, Ahmed M, Amran MS, Islam A, antidiabetic and glycogenesis effects of different fractions of ethanolic extract of leaves of Mangifera indica (Linn.) in Normal and Alloxan induced diabetic Rats. Journal of Medical Sciences 2010 10(4): 80-86

21. Rao NK, Nammi S, Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula retz. seeds in streptozotocin induced diabetic rats.l Bio Med Central Complementary and Alternative Medicine May 2006 6: 17

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23. Al-Snafi AE, Areview onCyperus rotundus A potential medicinal plant. IOSR Journal of Pharmacy july 2016 6(7): 32-48

24. Jarald E, Joshi S B, Jain D C, Biochemical study on the hypoglycemic effects of extract and fraction of Acacia catechu willed in Alloxan induced diabetic rats. Int J Diabetes & Metabolism 2009 17: 63-69

25. Semwal BC, Gupta J, Singh S, Kumar Y, Giri M, Antyhyperglycemic activity of root of Berberis Aristata dc in Alloxan induced diabetic Rats.International Journal of Green Pharmacy 2009 3(90): 155-60

26. Jeykodi S, Deshpande J, Juturu V, Salacia extract improves Postprandial glucose and Insulin response: A Randomised double blind placebo controlled crossover study in healthy volunteers. Journal of Diabetes Research 2016 9pages

27. Khatib NA, Patil PA, Evaluation of hypoglycemic activity of Barringtonia acutungula fruit exrracts in streptozotocin induced hyperglycemic wistar rats. Journal of Cell and Tissue research 2011 Vol 11(1): 2573-2578

28. Zhang H, Wei J, Xue R, Wu JD, Zhao W, Wang ZZ, et al Berberin lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.Metabolism Clinical and experimental Feb 2010 59(2): 285-292

29. Rasioanaivo P. Wright CW Willcox ML Gilbert B, Whole plant extract versus single compound for the treatment of Malaria: Synergy and positive interactions.Malaria Journal 2011 Vol 10(1) S1-S4.

Category: Volume 7 Issue 4 [July -Aug. 2017]

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Scientific Exploration of Ingredients of katak Khadiradi Kashyayamfor Their Anti Diabetic Property

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freeing items	0.07 ms
cleaning up	0.05 ms

id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	a	NULL	ref	idx_access,idx_state,idx_catid,idx_language	idx_catid	4	const	33	16.00	Using index condition; Using where; Using filesort
1	SIMPLE	cc	NULL	const	PRIMARY	PRIMARY	4	const	1	100.00	NULL

Status	Duration
starting	0.11 ms
checking permissions	0.00 ms
checking permissions	0.00 ms
checking permissions	0.00 ms
checking permissions	0.00 ms
checking permissions	0.00 ms
Opening tables	0.16 ms
init	0.04 ms
System lock	0.01 ms
optimizing	0.02 ms
statistics	0.15 ms
executing	0.01 ms
end	0.00 ms
query end	0.00 ms
closing tables	0.02 ms
freeing items	0.02 ms
cleaning up	0.04 ms

id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	m	NULL	ref	PRIMARY,published,newsfeeds,idx_language	published	1	const	12	3.33	Using index condition; Using where; Using filesort
1	SIMPLE	e	NULL	ref	element_clientid,element_folder_clientid	element_clientid	403	rajourna_ijahm.m.module,const	1	10.00	Using index condition; Using where
1	SIMPLE	mm	NULL	ref	PRIMARY	PRIMARY	4	rajourna_ijahm.m.id	1	40.00	Using where; Using index