Formulation And Evaluation of Poly Herbal Anti-Diabetic Tablet Dosage Form

Published: Saturday, 13 September 2014 10:43 | Written by Super User | Print | Email | Hits: 8225

D. Mamatha*

DOI : http://dx.doi.org/10.18535/ijahm/v7i6.06

Gland Institute of Pharmaceutical Sciences, Shangri-La, Kothapet (V), Sivampet (M) Near Narsapur,

Medak (Dist.)-502110, Telangana State, India

ABSTRACT:-

The main aim of the work is to formulate and evaluate poly herbal anti diabetic tablets for medicinal purpose by using Momordica charantia, Mangifera indica, Carica papaya, Syzygium cumini leaves were collected from the local area, dried, powdered and extracted with ethanol separately and stored for further use. Tablets were prepared after preformulation studies and tablets were evaluated by using Weight variation, Hardness, Friability, Thickness and Disintegration Time.

Results: Prepared granules by wet granulation method were performed preformulation studies based on the preformulation studies powder flow properties are good and Weight variation was ± 5%, Hardness, Friability are respectively 3.5 ± 0.43 kg/cm2, 0.58 ± 0.05%. Thickness was measured as 3 ± 0.02 mm and Disintegration time 6 ± 0.32 min are good.

Discussion and Conclusion: Now a day’s Herbal medicines plays major role in the treatment than allopathic medicines because of less toxicity. Momordica charantia, Mangifera indica, Carica papaya, Syzygium cumini ethanolic extracts were used to formulate tablets. Based on the results it is clearly concluded that the prepared formulation of poly herbal antidiabetic tablets and evaluations are good.

Key words: poly herbal, Momordica charantia, Mangifera indica, Carica papaya,Syzygium cumini anti diabetic tablet, Disintegration time.

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Category: Volume 7 Issue 6 (Nov- Dec 2017)

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Formulation And Evaluation of Poly Herbal Anti-Diabetic Tablet Dosage Form

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checking permissions	0.00 ms
Opening tables	0.26 ms
init	0.06 ms
System lock	0.01 ms
optimizing	0.02 ms
statistics	0.13 ms
preparing	0.03 ms
Creating tmp table	0.07 ms
Sorting result	0.01 ms
executing	0.00 ms
Sending data	0.29 ms
Creating sort index	0.04 ms
end	0.01 ms
query end	0.01 ms
removing tmp table	0.06 ms
query end	0.00 ms
closing tables	0.01 ms
freeing items	0.04 ms
cleaning up	0.05 ms

id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	a	NULL	ref	idx_access,idx_state,idx_catid,idx_language	idx_catid	4	const	20	16.00	Using index condition; Using where; Using filesort
1	SIMPLE	cc	NULL	const	PRIMARY	PRIMARY	4	const	1	100.00	NULL

Status	Duration
starting	0.12 ms
checking permissions	0.01 ms
checking permissions	0.00 ms
Opening tables	0.02 ms
init	0.06 ms
System lock	0.01 ms
optimizing	0.02 ms
statistics	0.11 ms
preparing	0.02 ms
Sorting result	0.01 ms
executing	0.00 ms
Sending data	0.01 ms
Creating sort index	0.27 ms
end	0.00 ms
query end	0.00 ms
closing tables	0.05 ms
freeing items	0.03 ms
cleaning up	0.01 ms

id	select_type	table	partitions	type	possible_keys	key	key_len	ref	rows	filtered	Extra
1	SIMPLE	m	NULL	ref	PRIMARY,published,newsfeeds,idx_language	published	1	const	12	3.33	Using index condition; Using where; Using filesort
1	SIMPLE	e	NULL	ref	element_clientid,element_folder_clientid	element_clientid	403	rajourna_ijahm.m.module,const	1	10.00	Using index condition; Using where
1	SIMPLE	mm	NULL	ref	PRIMARY	PRIMARY	4	rajourna_ijahm.m.id	1	40.00	Using where; Using index