¹Jemimma, H. L., ²Arumugasamy K , ³Nantha Kumar. R. , ⁴Abdul Kaffoor H.

DOI : http://dx.doi.org/10.18535/ijahm/v7i4.06

Department of Botany, Kongunadu Arts and Science College (Autonoumous), Coimbatore, Tamilnadu, India

ABSTRACT:

Objective: The objective of this research is to determine the possible bioactive components of the root and aerial parts of Phyllanthus vaukii using GC-MS analysis.

Methods: The GC-MS analysis of these extracts were performed using a Perkin-Elmer GC Clarus 500 system and Gas chromatograph interfaced to a Mass spectrometer (GC-MS) equipped with a BR-5MS, fused silica capillary column (30mm × 0.25mm 1D × 0.25 µMdf, composed of 5% Diphenyl / 95% Dimethyl poly siloxane).

Results: From P. vasukii root and aerial parts, thirty (30) and twenty seven (27) components were identified respectively. Of the 30 compounds  eluted from the root extract, stigmasterol had the highest peak area of 18% and the lowest was n-Propyl 11-octadecenoate showing 0.38%. In the aerial extract 1,2,3-Benzenetriol had the highest peak area of 31.65% and Z,Z-3,15-Octadecadien-1-ol acetate with the lowest peak area of 0.19%. These results indicate the ethanol extract of P. vasukii aerial and root parts possess potent antioxidant, hepatoprotective, anti-inflammatory, antiarthritic, antioxidant, anticancer, Immunostimulant, antitumour, cancer preventive, antiarthritic, antidiabetic, antimicrobial effects so that it can be recommended as a plant of pharmaceutical importance.

Conclusion: However, isolation of individual phytochemical constituents may proceed to find a novel drug or lead compound.

Keywords- Phyllanthus vasukii (P.vasukii), Gc-Ms Analysis, Bioactive Compound, root and aerial parts, ethanolic extract

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