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K Aruna Gayathri*1, K.V. RamSubbarao 2 , K.Ramanjaneyulu3
Aruna Gayithri.K*1. Assistant professor, P.G. Dept of Kaya chikitsa, Dr.B.R.K.R.Govt. Ayurvedic College Hyderabad,Telangana- 500038.
RamSubbarao. K.V2.Assistant Research Officer, Govt Research Dept(Ayurveda),Erragadda, Hyderabad, Telangana- 500038.
Analgesic and anti- inflammatory activity for herbomineral formulation was evaluated by using hot plate method. Crude extract of herbomineral formulation was prepared by using tween 80.2 % crude drugs which is present in the form of suspension was administered through oral route at a dose of 100 mg/kg, 200 mg/kg in mice weighing between 20-25 g using oral gavage and evaluated for analgesic activity at different time intervals such as 0, 15, 30, 60 and 90 minutes against standard (Tramadol Hydrochloride 22.8 mg/kg i.p) and control group, P< 0.05 was considered as significant. At a dose 100 mg/kg herbomineral formulation had shown significant activity10.00 ± 1.10 (P < 0.001), 200 mg/kg had shown significant activity at15, 30, 60 and 90 min time interval (P<0.001).
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