K Aruna Gayathri^*1, K.V. RamSubbarao ² ,   K.Ramanjaneyulu³

Paper Index :03.2015-xxxxxxx

Aruna Gayithri.K^*1. Assistant professor, P.G. Dept of Kaya chikitsa, Dr.B.R.K.R.Govt. Ayurvedic College Hyderabad,Telangana-  500038.

RamSubbarao. K.V².Assistant Research Officer, Govt Research Dept(Ayurveda),Erragadda, Hyderabad, Telangana- 500038.

Abstract

Analgesic and anti- inflammatory activity for herbomineral formulation was evaluated by using hot plate method. Crude extract of herbomineral formulation was prepared by using tween 80.2 % crude drugs which is present in the form of suspension was administered through oral route at a dose of 100 mg/kg, 200 mg/kg in mice weighing between 20-25 g using oral gavage and evaluated for analgesic activity at different time intervals such as 0, 15, 30, 60 and 90 minutes against standard (Tramadol Hydrochloride 22.8 mg/kg i.p) and control group, P< 0.05 was considered as significant. At a dose 100 mg/kg herbomineral formulation had shown significant activity10.00 ± 1.10 (P < 0.001), 200 mg/kg had shown significant activity at15, 30, 60 and 90 min time interval (P<0.001).

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