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Dr. Ninad Sathe1, Dr. Rohit Chavan2, Dr. Mujahid Khan3, Dr. Ashish punde4
1.Professor, Dept. of Rasashastra & Bhaishajyakalpana, YMT Ayurvedic Medical College, Kharghar, Navi Mumbai,
2,3.MD (Rasashastra & Bhaishajyakalpana)
4.Assistant professor, Dept. of Rasashastra & Bhaishajyakalpana, YMT Ayurvedic Medical
College, Kharghar, Navi Mumbai,
Herbo-mineral formulations are gaining negative propaganda in population. Hence, mankind can remain deficient from the bounty of effective and efficient ayurvedic formulation like makardhawaja. It is used as a rejuvenating & aphrodisiac (rasayan and vajikaran) drug. Modern medicine evolved a method of subjecting all assumptions to experimental verification and statistical validation. Therefore, current research had been undertaken with an aim to study cytotoxicity against selected MCF-7 human cell lines. Makardhwaj was prepared according to the reference of rasachandanshu which is a herbo-mineral formulation. Its cytotoxicity study was conducted at ACTREC. The solvent used for dissolution of the study drug was DMSO. Human cancer cell lines MCF-7 of breast were cryopreserved in liquid nitrogen and DMSO at -20 0C. Cell culture was performed in incubators at 37°C .The selected cell lines were inoculated in 96 well plates, in which study drug was tested at 4 dose levels i.e. 10, 20, 40, 80 µg/ml. Adriamycin was used as a positive control drug for comparative screening. According to SRB assay protocol Lc50values were calculated as declared by NCI. The study had revealed that, makardhwaja is not cytotoxic as the observed LC50 values were found > 80 in the study.
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12.Evaluation Of In Vitro Anticancer Activity of Hydroalcoholic Extract Of Taebernaemontana Divaricate. Akhilasravyadantu, Shankarguru P, Ramya Devi D, Vedhahari BN* Department Of Pharmaceutical Technology, School Of Chemical and Bio-Technology, SASTRA University, Thanjavur, 613401, (T.N.), India.
13.Evaluation Of Some Plant Extracts For Standardization And Anticancer Activity SN Gaidhani1*, Arjun Singh1, Suman Kumari1, GS Lavekar1, AS Juvekar2, S Sen2 & MM Padhi1 1Central Council For Research In Ayurvedic Sciences, 61-65, Institutional Area, Opposite ‘D’ Block, Janakpuri, New Delhi; 2Advance Centre For Treatment, Research And Education In Cancer (ACTREC), Kharger, Navi Mumbai-410 210, India.
14.Anticancer Potential Of The Convolvulus Arvensismanbir Kaur1, A.N.Kalia2 I.S.F. College Of Pharmaceutical Sciences And Research, Moga1,2 Punjab.
15.Anticancer And Antioxidant Activities Of Standardized Whole Fruit, Pulp, And Peel Extracts Of Egyptian Pomegranate Amira Abdel Motaal*,A And Sherifshakerb A Pharmacognosy Department, Faculty Of Pharmacy, Cairo University, Kasr-El-Ainy St., Cairo 11562, Egypt Bpharmaceutical Research And Development Department, Atos Pharma, Sekem, 3 Cairo-Belbeis Road, El Horreya, Cairo, P.B. 2834, Egypt.
16.Anti-Cancer And Anti-Microbial Activity Of Hydro Alcoholic Extract Of Bougainvillea Glabra Joshny J, Ramya Devi D, *Vedhahari B.N Department Of Pharmaceutical Technology, School Of Chemical And Bio-Technology, SASTRA University, Thanjavur, 613401, (T.N.). India.
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a. PGP College of Pharmaceutical Sciences and Institute Nammakal, Tamilnadu
b. JKKMMRF College of Pharmacy
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