¹Dr. Chawla Kumar Satbir , ²Dr. Priyanka

DOI : http://dx.doi.org/10.18535/ijahm/v7i4.27

^*1. Lecturer, Agad tantra Department, Glocal college of Ayurvedic Medical sciences and      research centre, Saharanpur, Uttar Pradesh, India.

^2. Lecturer, Stri Roga and Prasuti tantra Department, Chaudhary Devi Lal college of Ayurveda, Yamuna Nagar, Haryana, India.

Corresponding author:- Dr. Satbir Kumar Chawla 

H.No. 691, Sector 17, Huda, Jgadhari, Yamuna Nagar, Haryana, India

ABSTRACT:

Madatyaya is a (Vyadhi) disease mention by Ayurvedacharyas and in contemporary science it is correlated with “Alcoholism”. Now days it is spreading like an evil in the society. The present study deals with assessment of the clinical effect of “Punarnavadi Ghritta” in the management of “Madatyaya” w.s.r. to withdrawal symptom. In the study particular symptoms of Madataya are assessed on the basis of a self prepared gradation index. Blood Examinations Hb gm%, TLC, DLC, ESR, LFT are done to assess the efficacy of the drug. For clinical study a randomized open clinical trial of 30 days on 30 patients in Drug De-addiction was conducted where patients were assessed before treatment, on follow-up on 15^th day and after treatment. The patients were treated with Punarnavadi Ghritta. The before treatment and after treatment comparison of data reveals that treatment given to 30 patients shows significant (P<0.05) results in most of subjective parameters and objective parameters. The study revealed that the test drug Punarnavadi Ghritta is effective in improvement of sign symptoms and laboratory investigations in the patients of withdrawal symptoms of madatyaya.

Key words: Madatyaya, Sign and symptoms, Punarnavadi, Ghritta-

Reference:

      1.  Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda ipika commentary of  Chakrapanidatta, Edited           by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009, Varanasi: Chaukhmba Subharti  Prakashan; Chikitsa Sthan, 24/26,27.                    p.-583.

2.  Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda Dipika commentary of Chakrapanidatta, edited by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009, Varanasi: Chaukhmba Subharti Prakashan, Chikitsa Sthan, 24/8,9,10 p.- 582

3.   Raja Radhakantadeva Brahmdurega, Shabdakalpadruma; Edited by: Sri Vardha Parasada Vasuna, Delhi; Naag Publishers, Tritya Kaand,p.-588.

4.  Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda Dipika commentary of Chakrapanidatta, Edited by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009, Varanasi: Chaukhmba Subharti Prakashan; Chikitsa Sthan, 24/101-106, p.-587.

5. Harrison. Harrison’s Principles of Internal Medicine, 16th edition 2005, Edited by: Dennis L.Kasper, Eugene Braunwald,Vol.2nd, New Delhi;McGraw-Hill Medical Publishing Division, Section 6, 372,Alcohol and Alcoholism, p.-2565.

6.   Sushruta. Sushruta samhita. Edited by: Kaviraja Ambikadutta Shastri. 14th edition,Reprint:2003. Varanasi :Chakhamba Sanskrit Sansthan, Kalpasthana, 2/19-20, p.-24 .

7.  Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda Dipika commentary of Chakrapanidatta, edited by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009 Varanasi: Chaukhmba Subharti Prakashan, Chikitsa Sthan, 23/24, p.-572.

8.   Agnivesha. Charaka Smahita. Hindi commentary by: Acharya Vidyadhar Shukla and Prof. Ravi Dutt Tripathi, Reprint:2002. Varanasi: Chaukhmba Publication, Chikitsa Sathan , 24/32-34, p.-582.

9.   Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda Dipika commentary of Chakrapanidatta, Edited by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009, Varanasi: Chaukhmba Subharti Prakashan; Chikitsa Sthan, 24/90,94,96,  p.-587.

10. Agnivesha. Charaka Smahita, revised by Charaka and Dridhabala, with Ayurveda Dipika commentary of Chakrapanidatta, edited by: Vaidya Jadavaji Trikamji Acharya. Reprint:2009 Varanasi: Chaukhmba Subharti Prakashan, Chikitsa Sthan, 24 p.-587-591.

11.  Chakardatt. Padarthbodhini Hindi commentary by Pt. Ravidatt Shashtri, 2nd edition. Reprint:2005 Varanasi: Chaukhamba Publication,Chapter:18/10, p.84.

12.  Mahajan B.K.; Methods in Biostatistics; revised by Arun Bhadra Khanel; vii edition, reprint 2010; New Delhi; Jaypee Brothera Medical Publishers, Ch.8.p.112.

13.  Vriddhajivaka, Kashyapa Samhita; revised by Vatsya, with hindi commentary by Sri Satyapala Bhisagacharya, 10thedition, reprint:2005, Varanasi: Chaukhamba Sanskrit Sansthan; Chikitsa Sathan, Madataya/13-15.p.-136.

14.  The Ayurvedic Pharmacopoeia of India, Ministry of Health and Family Welfare, 2001, Part-1st, Vol.3rd, Delhi: The Controller of Publications, p.-158.

15.  The Ayurvedic Pharmacopoeia of India, Ministry of Health and Family Welfare, 2001, Part-1st, Vol.1st, Delhi: The Controller Of Publications, p.-128.

16.  Agnivesha. Charaka Smahita. Hindi commentary by: Acharya Vidyadhar Shukla and Prof. Ravi Dutt Tripathi, Reprint:2002. Varanasi: Chaukhmba Publication, Sutra Sathan,  27/217-18 p.-410.

17.  Agnivesha. Charaka Smahita. Hindi commentary by: Acharya Vidyadhar Shukla and Prof. Ravi Dutt Tripathi, Reprint:2002. Varanasi: Chaukhmba Publication, Sutra Sathan,  27/231-232 p.-411