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1Aliya Parveen , 2Dr Zarnigar
1Assistant Professor, Department of Community Medicine,RUMCHRC,Jaipur Rajasthan
2Lecturer, Department of Community Medicine,NIUM,Bangaluru,
Objectives: To assess the efficacy of Aabresham (Bombyx mori) for the prevention of atherosclerosis.
Methods: Randomized single blind standard control risk factor trial was conducted in National Institute of Unani Medicine Hospital, Bangalore from March 2015 to March 2016.
Fifty patients with risks of atherosclerosis were selected and randomly assigned into two groups 30 in test group and 20 in control group. Test group was treated with the decoction of Aabresham (Bombyx mori), six grams in the morning empty stomach for two months and control group was treated with Atorvastatin, ten mg, in the evening for the same duration. The response was evaluated by the assessing the subjective and objective parameters. The result was analyzed statistically by using Fisher Exact test, Chi-Square test and Student‘t’ test (Unpaired & Paired).
Results: Test group showed significant reduction in breathlessness, palpitation, headache, blood pressure, serum cholesterol, Low density lipoprotein (LDL) & MDA (Malonedialdehyde)
concentration (p<0.01) but chest pain, serum triglyceride, haematocrit and HDL(High density lipoprotein) values were found statistically insignificant in both groups. Overall, improvement was observed in test group except blood urea.
Conclusion: Aabresham(Bombyx mori shown to have an astounding potential in the prevention of atherosclerosis. It’s anti-oxidant, anti inflammatory, platelet stabilizing and anti- arrhythmic effect plays an unparallel role in the inhibition of development & progression of atherosclerosis. Integration with regimental therapies and dietary modification will potentiate its efficacy.
Keywords: Atherosclerosis, Marz-e-majari, Sudda, Aabresham
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