^Back To Top

foto1 foto2 foto3 foto4 foto5

Impact Factor : 4.415 ...... IJAHM Latest Issue IJAHM have published its latest issue Vol. 8 Issue 02 2018 published IJAHM Call For Paper invites paper from various Ayurveda & herbal Medicine for Volume 8 Issue 02 March-April. 2018

Mrs. S.Sameema Begum *, Dr.Ajithadhas Aruna, Dr.T.Sivakumar, Dr.C.Premanand, Mrs. C.Sribhuaneswari

Paper Index :05.2015-xxxxxxx

Nandha College of Pharmacy- Erode, Tamil Nadu


The study was aimed to evaluation of the anticancer (liver cancer) activity of the leaves of Ipomoea pes-tigridis against liver HEPG2 Cell line. The leaves of Ipomoea pes-tigridis hydro alcoholic extract were tested for its inhibitory effect on HEPG2 Cell Line. The percentage viability of the cell line and the cytotoxicity activity of Ipomoea pes-tigridis against HEPG2 Cell line was carried out by using MTT assay method. Ipomoea pes-tigridis ethanolic extract has significant cytotoxicity effect on HEPG2 Cell Line in the concentration range at 500µg/mL produce 99.87% of cell inhibition. From the above performed assay, ethanolic extract of these drug shows greater activity on HEPG2 cell line that means Ipomoea pestigridis can be used as anticancer activity particularly for liver cancer


1. WHO, Diet, nutrition and the prevention of chronic diseases (world health organisation, technical report series), 916, WHO, Geneva 2003.

2. Ekin NL, A Hausa herbal pharmacopoeia: Biomedical evaluation of commonly used plant medicines, Journal of pharmacology, 1981:4,75-78.

3. Sanjay Patel, Niravgheewala, Ashok Suthar, Anand Shah. Invitro cytotoxicity activity of solanum extract against Hella Cell Line and Vero Cell line. International journal of pharmacy and pharmaceutical sciences, 2009:1, 1.

4. Zhong YZ. Review about mechanisms of anticancer of solanum nigrum. Zhongguo 2006; 15: 1225-6, 1260.

5.Prasanth NV , Dilip C, Sanaldev KT, Lisaugustine, Saraswathi  R. Evalution of invitro cytotoxic and antioxidant activities of Ipomoea batatas. Int J Pharmacy& Pharm Sci 2010; 1(3).

6.Ramalingam R, Sivakumar T. Invitro and invivo anticancer activity of leaves of Plumeria alba Linn. J. Pharm. Res 2009; 2(2): 203-207.

7.PubMed Health www.ncbi.nlm.nih.gov.

8.Wikipedia, the free encyclopedia en.wikipedia.org/wiki/Hep_G

9.Matthew KM. The Flora of the Tamil Nadu Carnatic 1981; 2: 1017-1033.

10.Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants 1956: 141-142.

11.Sharma DP. Studies on nutritional qualities of Ipomoea pes-tigiridis Linn; a fodder plant from Kunvari Ravin land at Morena (MP) India. Asian J Chem 2002; 14(2): 1119-1121.

12.Hamsa TP, Kuttan G. Antioxidant activity of Ipomoea obscura. Amala Research Bulletin 2007; 27: 24-34.

13.Vimala Y, Elizabeth KM, Srilakshmi Selvi G. Antimicrobial activity of Ipomoea kentrochules on pathogenic microorganisms and microbial isolates on spoiled vegetables. Asian J Micro, Biotech & Environmental Sci 2007; (1): 41-44.

14.Khare AK, Srivastava MC, Tewa JP, Puri JN, Singh S, Ansari NA. A preliminary study of anti-inflammatory activity of Ipomoea turpethium (NISHOTH). Indian Drugs 1982; 19(6): 224-228.

15.Da Silvo Filho AA, Correa Lima RMO, De Andrade Chiapett A, Do Nascimento SC, De Souza IA, Demello JF, Veith HJ. Anticancer and antimicrobial glycosides from Ipomoea bahiensis. Phytochem 1986; 25(5): 1077-1081.


16.Navarro-Ruiz A, Delamora GP, Villanuev Michel MI, Dominguez JR, Bastidas-Ramirez BE, Quezada-Arellano JD, Rui Madrigal B. Anticonvulsant effect of aqueous, hydro alcohol and chloroform extracts from Ipomoea stans root in the rat. Phytotheraphy Res 1996;  10(3): 242-244.

17.Ferreria AA, Amarlal FA, Durate IDG, Oliveria PM, Alves RB, Silveria D, Azevedo AO, Raslan DS, Castro MSA. Antinociceptive effect from Ipomoea cairica extract. J Ethnopharmacol 2006; 105(1-2): 148-153.

18.Cordell GA. Phytochemistry 1995; 40: 1585-1612.

19.Harnburger M, Hostettmann K. Phytochemistry 1991;30: 3864-3874.


20.Kusumoto IT, Nakabayashi T, Kida H, Miyashiro h, Hattori M, Namba T, Shimotohna K. Screenung of various plant extracts used in ayurvedic medicine for inhibitory effects on human immune deficiency virus type I(HIV-I) protease. Phytotherapy Rearch 1995; 9: 180-184.

IJAHM Content



Crossref - DOI

DOI : 10.31142/ijahm

Impact Factor



Who's Online

We have 29 guests and no members online


 Copyright © 2018 IJAHM  Rights Reserved.